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Download A Clinical Guide for Contraception by Leon Speroff MD, Philip D. Darney MD MSc PDF

By Leon Speroff MD, Philip D. Darney MD MSc

"The completely up-to-date 5th version of this useful instruction manual is a present, trustworthy, and readable consultant to the clever use of brand new contraceptive recommendations. The authors give you the crucial info that clinicians and sufferers have to decide upon the simplest contraceptive process for the patient's age and clinical, social, and private features. The booklet concisely covers all to be had medications and devices. Read more...


A advisor to the clever use of contraceptive strategies. It bargains info that clinicians and sufferers have to pick out the simplest contraceptive technique for the patient's age and scientific, social, and Read more...

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Example text

48 A statistically significant reduction associated with Yasmin treatment was achieved in only one category, that measuring acne, appetite, and food cravings. The overall result was essentially not significant. 49 Marvelon was associated with a small increase in body weight after the fifth cycle; the average body weight associated with Yasmin remained throughout the 2 years below the baseline level at the beginning of the study, but increased to a level above the baseline at the end of the study.

From 1962 to 1966, Chang and Pincus were pursuing a drug that could prevent pregnancy with one administration, a day or two after sexual intercourse. With Pincus’s death, this project was abandoned. It is not certain whether Chang and Pincus coined the phrase the “morning after” pill, but it is accurate to state that the concept came from Chang. When Pincus and Chang began their studies, the focus was on inhibition of ovulation, first by progesterone, and then by synthetic progestins. Chang’s contribution was easy to overlook.

53 This approach minimizes estrogen exposure at the beginning of the cycle, yielding a low rate of side effects such as nausea. 54,55 Extended Regimens Two clinical concerns prompted the development of an oral contraceptive regimen with a reduction in the pill-free interval: (1) breakthrough bleeding, and (2) ovarian activity during pill taking that could lead to ovulation and failure of contraception. Extending the active pill cycle by several days is aimed at decreasing breakthrough bleeding and spotting and reducing the length of withdrawal bleeding without compromising efficacy or safety, and perhaps increasing contraceptive protection by a greater suppression of ovarian activity.

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